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1

PI-3K/Akt signal pathway plays a crucial role in arsenite-induced cell proliferation of human keratinocytes through induction of cyclin D1

Weiming Ouyang, Jingxia Li, Dongyun Zhang, Bing-Hua Jiang, Dr Chuanshu Huang

Journal:

Journal of Cellular Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 276 KB

english, 2007

2

The Biological Functions of NF-κB1 (p ) and its Potential as an Anti-Cancer Target

Yu, Yonghui, Wan, Yu, Huang, Chuanshu

Journal:

Current Cancer Drug Targets

Année:

2009

Langue:

english

Fichier:

PDF, 173 KB

english, 2009

3

Anti-cancer Drug Discovery: Update and Comparisons in Yeast, Drosophila, and Zebrafish

Gao, Guangxun, Chen, Liang, Huang, Chuanshu

Journal:

Current Molecular Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 176 KB

english, 2015

4

Inhibition of atypical PKC blocks ultraviolet-induced AP-1 activation by specifically inhibiting ERKs activation

Chuanshu Huang, Jingxia Li, Nanyue Chen, Wei-ya Ma, G. Tim Bowden, Zigang Dong

Journal:

Molecular Carcinogenesis

Année:

2000

Langue:

english

Fichier:

PDF, 261 KB

english, 2000

5

Inhibition of Ultraviolet B–Induced AP-1 Activation by Theaflavins From Black Tea

Masaaki Nomura, Wei-Ya Ma, Chuanshu Huang, Chung S. Yang, G. Tim Bowden, Ken-ichi Miyamoto, Zigang Dong

Journal:

Molecular Carcinogenesis

Année:

2000

Langue:

english

Fichier:

PDF, 222 KB

english, 2000

6

Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells

Jingxia Li, Lun Song, Dongyun Zhang, Lixin Wei, Chuanshu Huang

Journal:

Journal of Cellular Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 286 KB

english, 2006

7

Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species

Liying Wang, Djordje Medan, Robert Mercer, Dean Overmiller, Stephen Leornard, Vincent Castranova, Xianglin Shi, Min Ding, Chuanshu Huang, Yon Rojanasakul

Journal:

Journal of Cellular Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 405 KB

english, 2003

8

Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKα-dependent cyclin D1 down-regulation

Weiming Ouyang, Dongyun Zhang, Jingxia Li, Udit N. Verma, Max Costa, Chuanshu Huang

Journal:

Journal of Cellular Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 484 KB

english, 2009

9

Involvement of c-jun NH2-terminal kinases in resveratrol-induced activation of p53 and apoptosis

Qing-Bai She, Chuanshu Huang, Yiguo Zhang, Zigang Dong

Journal:

Molecular Carcinogenesis

Année:

2002

Langue:

english

Fichier:

PDF, 134 KB

english, 2002

10

Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-κB in mouse epidermal cl41 cells

Jingxia Li, Haobin Chen, Qingdong Ke, Zhaohui Feng, Moon-Shong Tang, Bingci Liu, Shantu Amin, Max Costa, Chuanshu Huang

Journal:

Molecular Carcinogenesis

Année:

2004

Langue:

english

Fichier:

PDF, 394 KB

english, 2004

11

Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKβ/NF-κB in mouse epidermal Cl41 cells

Weiming Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang, Jin Ding, Yi Huang, Mingzhao Xing, Chuanshu Huang

Journal:

Molecular Carcinogenesis

Année:

2007

Langue:

english

Fichier:

PDF, 349 KB

english, 2007

12

Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes

Jingxia Li, Dongyun Zhang, Gary D. Stoner, Chuanshu Huang

Journal:

Molecular Carcinogenesis

Année:

2008

Langue:

english

Fichier:

PDF, 336 KB

english, 2008

13

Downregulation of cyclin D1–CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway

Fuhai Shen, Xueyun Fan, Bingci Liu, Xiaowei Jia, Ai Gao, Hongju Du, Meng Ye, Baorong You, Chuanshu Huang, Xianglin Shi

Journal:

Cell Biology International

Année:

2008

Langue:

english

Fichier:

PDF, 525 KB

english, 2008

14

Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways

Jisen Dai, Chuanshu Huang, Jing Wu, Chengfeng Yang, Krystyna Frenkel, Xi Huang

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 275 KB

english, 2004

15

Vanadate-induced cell growth arrest is p53-dependent through activation of p21 in C141 cells

Zhuo Zhang, Chuanshu Huang, Jinxia Li, Xianglin Shi

Journal:

Journal of Inorganic Biochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 334 KB

english, 2002

16

Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression

Wei Guo, Zhuo Yang, Qing Xia, Jinyi Liu, Yonghui Yu, Jingxia Li, Zhenghong Zuo, Dongyun Zhang, Xueyong Li, Xianglin Shi, Chuanshu Huang

Journal:

Cellular and Molecular Life Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 780 KB

english, 2011

17

ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells

Jingxia Li, Qiangsong Tong, Xianglin Shi, Max Costa, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2005

18

Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression

Weiming Ouyang, Jingxia Li, Xianglin Shi, Max Costa, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2005

19

Carcinogenic effect of nickel compounds

Haitian Lu, Xianglin Shi, Max Costa, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 242 KB

english, 2005

20

Involvement of nuclear factor of activated T cells 3 (NFAT3) in cyclin D1 induction by B[a]PDE or B[a]PDE and ionizing radiation in mouse epidermal Cl 41 cells

Jin Ding, Ronghe Zhang, Jingxia Li, Caifang Xue, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 285 KB

english, 2006

21

NFAT3 is Required for EGF-Induced COX-2 Transcription, but Neither iNOS Transcription Nor Cell Transformation in Cl 41 Cells

Jingxia Li, Haitian Lu, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 341 KB

english, 2006

22

Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B

Dongyun Zhang, Haitian Lu, Jingxia Li, Xianglin Shi, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 451 KB

english, 2006

23

Effect of Microglia Activation on Dopaminergic Neuronal Injury Induced by Manganese, and Its Possible Mechanism

Mingchao Liu, Tongjian Cai, Fang Zhao, Gang Zheng, Qiang Wang, Yaoming Chen, Chuanshu Huang, Wenjing Luo, Jingyuan Chen

Journal:

Neurotoxicity Research

Année:

2009

Langue:

english

Fichier:

PDF, 519 KB

english, 2009

24

Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor-κB kinase β-subunit-/nuclear factor-κB is critical for cyclooxygenase-2 induction by benzo[a]pyrene in human bronchial epithelial cells

Jin Ding, Kangjian Wu, Dongyun Zhang, Wenjing Luo, Jingxia Li, Weiming Ouyang, Lun Song, Chuanshu Huang

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

25

Signal transduction through atypical PKCs, but not the EGF receptor, is necessary for UVC-induced AP-1 activation in immortal murine cells

Huang, Chuanshu, Ma, Wei-ya, Dong, Zigang

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 507 KB

english, 1997

26

Increased synthesis of phosphocholine is required for UV-induced AP-1 activation

Dong, Zigang, Huang, Chuanshu, Ma, Wei-Ya, Malewicz, Barbara, Baumann, Wolfgang J, Kiss, Zoltan

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 393 KB

english, 1998

27

Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation

Watts, Rebecca G, Huang, Chuanshu, Young, Matthew R, Li, Jian-Jian, Dong, Zigang, Pennie, William D, Colburn, Nancy H

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 316 KB

english, 1999

28

The extracellular-signal-regulated protein kinases (Erks) are required for UV-induced AP-1 activation in JB6 cells

Huang, Chuanshu, Ma, Wei-ya, Dong, Zigang

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 241 KB

english, 1999

29

Differential requirement of EGF receptor and its tyrosine kinase for AP-1 transactivation induced by EGF and TPA

Li, Jingxia, Ma, Cuiling, Huang, Yi, Luo, Jia, Huang, Chuanshu

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 212 KB

english, 2003

30

A critical role of PI-3K/Akt/JNKs pathway in benzo[a]pyrene diol-epoxide (B[a]PDE)-induced AP-1 transactivation in mouse epidermal Cl41 cells

Li, Jingxia, Tang, Moon-shong, Liu, Bingci, Shi, Xianglin, Huang, Chuanshu

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 387 KB

english, 2004

31

The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-κB

Xianglin Shi, Zigang Dong, Chuanshu Huang, Xianglin Shi, Wiya Ma, Kejian Liu, Fei Chen, Stephen S. Leonard, Min Ding, Vince Castranova, Val Vallyathan

Journal:

Molecular and Cellular Biochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 75 KB

english, 1999

32

Differential role of hydrogen peroxide in UV-induced signal transduction

Min Ding, Jingxia Lia, Stephen S. Leonard, Xianglin Shi, Max Costa, Vincent Castranova, Val Vallyathan, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 491 KB

english, 2002

33

Involvement of hydrogen peroxide in asbestos-induced NFAT activation

Jingxia Li, Bihui Huang, Xianglin Shi, Vincent Castranova, Val Vallyathan, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 140 KB

english, 2002

34

Involvement of Erks activation in cadmium‐induced AP‐1 transactivation in vitro and in vivo

Chuanshu Huang, Qunwei Zhang, Jingxia Li, Xianglin Shi, Vincent Castranova, Gong Ju, Max Costa, Zigang Dong

Journal:

Molecular and Cellular Biochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 91 KB

english, 2001

35

Arsenic‐induced NFκβ transactivation through Erks‐ and JNKs‐dependent pathways in mouse epidermal JB6 cells

Chuanshu Huang, Jingxia Li, Min Ding, Liying Wang, Xianglin Shi, Vincent Castranova, Val Vallyathan, Gong Ju, Max Costa

Journal:

Molecular and Cellular Biochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 109 KB

english, 2001

36

Transactivation of RARE and GRE in the cellular response to arsenic

Chuanshu Huang, Jingxia Li, Min Ding, Max Costa, Vincent Castranova, Val Vallyathan, Gong Ju, Xianglin Shi

Journal:

Molecular and Cellular Biochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 89 KB

english, 2001

37

Activation of a PKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6kin mouse epidermal JB6 cells

Jingxia Li, Sujatha Dokka, Liying Wang, Xianglin Shi, Vincent Castranova, Yan Yan, Max Costa, Chuanshu Huang

Journal:

Molecular and Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 133 KB

english, 2004

38

Vanadate activated PI3K and Akt and promoted S phase entry

Zhuo Zhang, Ning Gao, Hengyun He, Chuanshu Huang, Jia Luo, Xianglin Shi

Journal:

Molecular and Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 249 KB

english, 2004

39

Molecular mechanisms of arsenic carcinogenesis

Chuanshu Huang, Qingdong Ke, Max Costa, Xianglin Shi

Journal:

Molecular and Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 77 KB

english, 2004

40

The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry

Zhuo Zhang, Ning Gao, Hengyun He, Chuanshu Huang, Bing-hua Jiang, Luo Jia, Xianglin Shi

Journal:

Molecular and Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 250 KB

english, 2004

41

The immunoregulatory effect of TLSFJMon the expression of T cell IL-2R and protein tyrosine phosphorylation

Haibin Xia, Boquan Jin, Hui Xu, Ning Zhao, Xuesong Liu, Chuanshu Huang, Yong Zhu, Enshan Li

Journal:

Chinese Journal of Cancer Research

Année:

1991

Langue:

english

Fichier:

PDF, 279 KB

english, 1991

42

A novel role of IKKα in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression

Lun Song, Wen Dong, Ming Gao, Jingxia Li, Meiru Hu, Ning Guo, Chuanshu Huang

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2010

43

The role of epidermal growth factor receptor in ethanol-mediated inhibition of activator protein-1 transactivation

Cuiling Ma, Kimberly A. Bower, Hong Lin, Gang Chen, Chuanshu Huang, Xianglin Shi, Jia Luo

Journal:

Biochemical Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 423 KB

english, 2005

44

JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo

Zibo Song, Chang Tong, Jiao Liang, Ashley Dockendorff, Chuanshu Huang, Leonard H. Augenlicht, Wancai Yang

Journal:

European Journal of Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

45

Superoxide plays critical roles in electrotaxis of fibrosarcoma cells via activation of ERK and reorganization of the cytoskeleton

Fei Li, Hui Wang, Li Li, Chuanshu Huang, Jiangkai Lin, Gang Zhu, Zhi Chen, Nan Wu, Hua Feng

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2012

46

Nickel carcinogenesis: Epigenetics and hypoxia signaling

Max Costa, Todd L. Davidson, Haobin Chen, Qingdong Ke, Ping Zhang, Yan Yan, Chuanshu Huang, Thomas Kluz

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2005

Langue:

english

Fichier:

PDF, 568 KB

english, 2005

47

Cancer prevention with freeze-dried berries and berry components

Gary D. Stoner, Li-Shu Wang, Nancy Zikri, Tong Chen, Stephen S. Hecht, Chuanshu Huang, Christine Sardo, John F. Lechner

Journal:

Seminars in Cancer Biology

Année:

2007

Langue:

english

Fichier:

PDF, 297 KB

english, 2007

48

c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells

Dongyun Zhang, Jingxia Li, Jimin Gao, Chuanshu Huang

Journal:

Toxicology and Applied Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 513 KB

english, 2009

49

γ-aminobutyric acidA (GABAA) receptor regulates ERK1/2 phosphorylation in rat hippocampus in high doses of Methyl Tert-Butyl Ether (MTBE)-induced impairment of spatial memory

Gang Zheng, Wenbin Zhang, Yun Zhang, Yaoming Chen, Mingchao Liu, Ting Yao, Yanxia Yang, Fang Zhao, Jingxia Li, Chuanshu Huang, Wenjing Luo, Jingyuan Chen

Journal:

Toxicology and Applied Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 739 KB

english, 2009

50

Hypoxia-induced mitogenic factor enhances angiogenesis by promoting proliferation and migration of endothelial cells

Qiangsong Tong, Liduan Zheng, Bo Li, Danming Wang, Chuanshu Huang, George M. Matuschak, Dechun Li

Journal:

Experimental Cell Research

Année:

2006

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2006